News Febbraio

February 2014

Rapid Review Panel awards Clinell Alcoholic 2% Chlorhexidine Wipes Category One Status

GAMA are the only company in the UK who have been awarded with the Department of Health’s ‘RRP’ Category One Status for our clinical proven Clinell Alcoholic 2% Chlorhexidine wipes.

The Government Health Protection Agency founded the RRP in 2004 to help prevent and lower the rate of Healthcare Associated Infections (HCAIs). It is run by an independent panel of leading UK infection control experts and judges the benefits of products at the request of The Department of Health.

Clinell Alcoholic 2% Chlorhexidine Wipes are disposable disinfectant wipes used for the disinfection of non-invasive medical devices such as venous and arterial catheters, peripheral cannulas, needleless connectors and blood culture bottle caps. They are pre-saturated with 70% isopropyl alcohol and 2% chlorhexidine gluconate, conforming to the current EPIC 3 guidance (IVAD30).

The wipes provide fast acting and long lasting antimicrobial action with excellent residual activity. They are proven to be effective at disinfecting central venous catheter hubs, sampling ports and reduce catheter related blood stream bacteraemias. Alcohol and chlorhexidine have been shown to be more effective than both 70% alcohol and 10% povidone-iodine for preventing central venous and arterial catheter related infections.

Clinell Alcoholic 2% Chlorhexidine Wipes are now supported directly by GAMA Healthcare, which means improved support and training. Contact us or a member of our sales team to discuss our great deals.


Clinell’s FREE* comprehensive, training and support is now available for every type of wipe that your Trust uses. GAMA Healthcare is the only supplier on NHS Supply Chain that can provide every kind of wet or dry wipe listed.

Whether your Trust uses alcohol pre-injection swabs, patient wipes, surface wipes or multi-purpose dry wipes - you can trust GAMA Healthcare to provide quality, innovative products in addition to making a significant cost saving.

New ranges of Clinell Alcohol Wipes, Patient Wipes (Body Care and Hands and Face) are now available. We have also extended our market leading Universal and Detergent range.

GAMA are delighted to introduce Carell Patient Dry Wipes and Cleanall Professional Cleaning Cloths to complete our range of wipes. Carell’s soft, durable and absorbent dry wipes are ideal for patient and multi-purpose cleaning. Available in five types.

Cleanall general purpose cleaning cloths are colour coded to comply with national guidelines. Available in three sizes and weights.

Choosing GAMA not only means that you get the best wipes available, but you will also receive the best aftercare support. This includes FREE dispenser installation, FREE* revolutionary tablet-based Training Package, FREE on-site training from experienced infection control nurse trainers and FREE bespoke educational marketing support.

IPS annual conference and exhibition

This year  IPS annual conference and exhibition was based in our backyard at the ExCeL in London. The usual balance of informative talks, superb entertainment and the opportunity to meet old and new friend alike made it a great exhibition for us.

We were proud to introduce our complete range of wipes to the delegates. This includes our new Cleanallmulti purpose cleaning and CarellPatient Dry Wipes.

However the surprise hit for us at this year’s conference was our Safety Scalpelrange. The unique polymer coated blade, simple safety mechanism and comprehensive range of disposable and metal handles made it consistently the busiest ‘pod’ on our stand.

Our BATAK wall generated a lot of interest and truly showcased the competitive spirit of many delegates. A amazing time was had by all and we can’t wait for IPS 2014 in Glasgow.

Reduction of blood stream infections in children following a change to chlorhexidine disinfection of parenteral nutrition catheter connectors.


2013 Apr 10. pii: S0261-5614(13)00099-X. doi: 10.1016/j.clnu.2013.03.021. [Epub ahead of print]

Reduction of blood stream infections in children following a change to chlorhexidine disinfection of parenteral nutrition catheter connectors.


Department of Paediatric Gastroenterology, Great Ormond Street Hospital NHS Trust, London WC1N 3JH, UK; Department of Paediatric and Adolescent Medicine, Medical University of Vienna, Austria. Electronic address: Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo. .



Catheter-related-blood-stream-infection (CRBSI) might be prevented by optimal catheter connector antisepsis in children with intestinal failure on parenteral nutrition (PN). We changed the disinfectant used from isopropanol 70% to chlorhexidine 2% in 70% isopropanol, which leaves a residue of chlorhexidine on the connector.


We conducted this before/after study in children treated with PN for >28 days. Episodes of CRBSI were recorded for all 42 children treated for >28 days during May-November 2006 before introducing chlorhexidine and for all 50 children treated in May-November 2007 after chlorhexidine was introduced. The number of hospital-acquired CRBSI and number of PN days was counted for each period. The rate of CRBSI/1000 catheter days and the proportion of patients that experienced at least one CRBSI during the two periods were compared.


There were 3.1 CRBSI/1000 catheter days prior to using chlorhexidine and 0.4 CRBSI/1000 catheter days after it was introduced, p = 0.03. Prior to chlorhexidine 10/42 (24%) patients experienced at least one episode of CRBSI, compared to 3/50, (6%) after introducing it (p = 0.02). The survival rate in both periods was similar, but after chlorhexidine significantly more children made a full recovery and a lower proportion of children had irreversible intestinal failure (p = 0.01).


Our results support the use of 2% chlorhexidine not only to reduce risk of sepsis for central venous catheter connector antisepsis in catheters used for intravenous nutrition, but also to improve the patients' chances of recovering intestinal function.

Copyright © 2013 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

[PubMed - as supplied by publisher]



Clostridium difficile-Efficacia di Sporicidal

Efficacy of ‘‘sporicidal’’ wipes against

Clostridium difficile

Harsha Siani, BSc, Callum Cooper, BSc, and Jean-Yves Maillard, PhD

Cardiff, United Kingdom

Background: Hospital-acquired infections associated with Clostridium difficile cause severe morbidity and mortality. The current

control of C difficile endospores with liquid sporicides might have limited efficacy in the health care environment. Sporicidal wipes

might offer additional control of surface bioburden and are now increasingly used, although there is little information about their

efficacy against spores in practice.

Methods: Ten wipes were tested for sporicidal efficacy using a recently developed 3-stage protocol that measures the ability of the

wipe to remove microbial bioburden from a surface, the potential for microbial transfer from the wipe to other surfaces, and the

sporicidal activity of the wipe. Scanning electron microscopy was used to visualize the association of spores with the wipe fibers,

and light scattering was used to measure the size of spore aggregates released from the wipes.

Results: The ability of the sporicidal wipes to remove C difficile spores from an inanimate surface ranged from 0.22 to 4.09 log10

spores removed within 10 seconds. One wipe did not remove any spores. None of the wipes demonstrated high sporicidal activity

(ie, .4 log10 reduction) within 5 minutes of contact time, except for a control wipe soaked in 5,000-ppm sodium hypochlorite.

Only one wipe demonstrated some sporicidal activity after 5 minutes, with a 1.50 and a 3.74 log10 reduction in spore number

of C difficile NCTC12727 and R20291 (ribotype 027), respectively. All but one wipe demonstrated that spores could be repeatedly

transferred to other surfaces. Light-scattering data provided evidence that some wipes were able to break up spore aggregates, potentially

releasing more spores onto the surface. Electron microscopy micrographs showed that spores might be loosely associated

with some wipes, explaining the rapid release.

Conclusion: Although the use of sporicidal wipes might offer additional control of microbial burden on surfaces, current efficacy

tests might be inadequate to reflect the activity of these wipes in practice. This can lead to the use of wipes that might not be appropriate

for applications in the health care environment. Tighter control of labeling and appropriate efficacy tests are needed

before antimicrobial wipes are released to the market.

Key Words: Activity; surface disinfection; impregnated wipes; endospores.

Copyright ª 2011 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights

reserved. (Am J Infect Control 2011;39:212-8.)

Clostridium difficile has been associated with severe

morbidity and mortality in the health care environment.

The use of effective cleaning regimens and surface

disinfection helps minimize the spread of

pathogens and ultimately decrease the risk to patients

and staff. It also contributes to decreasing the financial

burden associated with treatment and longer hospital

stays.1-3 The persistence of C difficile endospores on

surfaces after disinfection2-5 presents an additional obstacle

to the successful implementation of cleaning/

disinfection procedures. Bacterial endospores are

considered among the most resistant life forms to surface

disinfection and sterilization6 because of their

structure and properties.7 Thus, all cleaning/disinfection

regimens need to be proven effective to prevent

the presence/survival and spread of spore-forming

pathogenic bacteria and other microorganisms.8-10 Although

sporicidal properties have been claimed for a

number of microbicides, only a few of these have a reportedly

rapid action (ie, within seconds).10 Hypochlorites

are among the most widely used disinfectants in

the health care environment.11 Sodium hypochlorite

has demonstrated some success in decreasing C difficile

incidence12,13 and surface contamination,14 but the efficacy

of liquid disinfectants is severely hampered by

the limited contact time that typically can be achieved

in a busy health care environment.

Antimicrobial wipes are increasingly used to clean/

disinfect surfaces proximal to patients in health care

settings. Some antimicrobial wipes purportedly have

a dual action, providing both cleaning and disinfection.

Such products might be efficacious in removing a microbial

bioburden from a surface; however, observations

of their use in hospitals indicate that their

antimicrobial activity might be limited due to short

application times and repeated use on multiple

From theWelsh School of Pharmacy, Cardiff University, Cardiff, United


Address correspondence to Jean-Yves Maillard, PhD, Welsh School of

Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10

3NB, United Kingdom. E-mail: Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo. .

Funding for this study was provided by GAMA Healthcare, London,

United Kingdom.

Conflict of interest: None to report.


Copyright ª 2011 by the Association for Professionals in Infection

Control and Epidemiology, Inc. Published by Elsevier Inc. All rights





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